Heart rate recovery after submaximal exercise testing as a predictor of mortality in a cardiovascularly healthy cohort
Heart rate recovery after submaximal exercise testing as a predictor of mortality in a cardiovascularly healthy cohort
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DOI：
10.7326/0003-4819-132-7-200004040-00007
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发表时间：
2000-04-04
影响因子：
39.2
通讯作者：
Lauer, MS
中科院分区：
文献类型：
--
作者：
Cole, CR;Foody, JM;Lauer, MS
Background: Abnormal heart rate recovery after symptom-limited exercise predicts death. It is unknown whether this is also true among patients undergoing submaximal testing.Objective: To test the prognostic implications of heart rate recovery in cardiovascularly healthy adults undergoing submaximal exercise testing.Design: Population-based cohort study.Setting: 10 primary care sites.Participants: 5234 adults without evidence of cardiovascular disease who were enrolled in the Lipid Research Clinics Prevalence Study.Measurements: Heart rate recovery was defined as the change from peak heart rate to that measured 2 minutes later (heart rate recovery was defined as less than or equal to 42 beats/min).Results: During 12 years of follow-up, 312 participants died. Abnormal heart rate recovery predicted death (relative risk, 2.58 [CI, 2.06 to 3.20]). After adjustment for standard risk factors, fitness, and resting and exercise heart rates, abnormal heart rate recovery remained predictive (adjusted relative risk, 1.55 [CI, 1.22 to 1.98]) (P < 0.001).Conclusion: Even after submaximal exercise, abnormal heart rate recovery predicts death.
