FATHERS DRINKING AND INFANT BIRTH-WEIGHT - REPORT OF AN ASSOCIATION
FATHERS DRINKING AND INFANT BIRTH-WEIGHT - REPORT OF AN ASSOCIATION
复制标题
DOI：
10.1002/tera.1420360109
复制
发表时间：
1987-08-01
期刊：
影响因子：
--
通讯作者：
SING, CF
中科院分区：
文献类型：
--
作者：
LITTLE, RE;SING, CF
对377名健康维护组织成员所生婴儿的父母在怀孕前一个月的饮酒情况进行了调查。如果父亲平均每天喝两杯或两杯以上，或者一次至少喝五杯，通过回归分析预测婴儿出生体重减少137克。这一结果与母亲饮酒无关，尽管母亲经常饮酒的婴儿出生时体重较轻。经常饮酒的父亲的婴儿平均出生体重较低，不是由于父母吸烟，母亲使用咖啡因，大麻或其他药物，或其他21个测量变量。这是第一份关于父亲在怀孕前饮酒与婴儿出生体重下降之间存在关联的人类报告。然而，对这一发现的解释是困难的，因为可能构成其基础的生物学机制尚不清楚。
Parents'' drinking in the month prior to conception was ascertained for 377 infants born to members of a health maintenance organization. If the father had an average of two or more drinks daily, or had at least five drinks on one occasion, a decrease of 137 gm in infant birth weight was predicted, by means of regression analysis. This result was independent of maternal drinking, although infants whose mothers were regular drinkers weighed less at birth. The lower mean birth weights of infants of regular-drinking fathers was not due to parents'' smoking, maternal use of caffeine, marijuana, or other drugs, or 21 other measured variables. This is the first report of an association in humans between father''s drinking prior to conception and decreased infant birth weight. However, interpretation of this finding is difficult because the biological mechanisms that might underlie it are obscure.