Diagnosis and therapy of sepsis.: Guidelines of the German Sepsis Society Inc and the German Interdisciplinary Society for Intensive and Emergency Medicine
Diagnosis and therapy of sepsis.: Guidelines of the German Sepsis Society Inc and the German Interdisciplinary Society for Intensive and Emergency Medicine
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DOI：
10.1007/s00108-006-1595-x
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发表时间：
2006-04-01
期刊：
影响因子：
--
通讯作者：
Werdan, K
中科院分区：
文献类型：
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作者：
Reinhart, K;Brunkhorst, F;Werdan, K
最近由公共资助的能力网络败血症（SepNet）进行的一项调查显示，在德国，每年有75，000名居民（110/100，000）发生严重败血症和/或败血性休克，79，000名居民（116/100，000）发生败血症。这种疾病导致大约60，000人死亡，是急性心肌梗死后第三大最常见的死亡原因。仅重症脓毒症患者重症监护的直接成本就高达约17.7亿欧元，这意味着重症监护预算的约30%用于治疗严重脓毒症。然而，到目前为止，德国还没有严重脓毒症的诊断和治疗指南。因此，德国脓毒症协会根据国际脓毒症论坛（ISF）和脓毒症生存运动（SSC）的国际建议，并考虑到德国医疗保健系统的结构和组织，开始制定指南。优先考虑以下指南主题：a）诊断，B）预防，c）病因治疗，d）支持治疗，e）预防治疗。该指南的制定过程经过精心规划，并严格遵守科学医学会工作组（AWMF）的要求。
A recent survey conducted by the publicly funded Competence Network Sepsis (SepNet) reveals that severe sepsis and/or septic shock occurs in 75,000 inhabitants (110 out of 100,000) and sepsis in 79,000 inhabitants (116 out of 100,000) in Germany annually. This illness is responsible for approximately 60,000 deaths and ranges as the third most frequent cause of death after acute myocardial infarction. Direct costs for the intensive care of patients with severe sepsis alone amount to approximately 1.77 billion euros, which means that about 30% of the budget in intensive care is used to treat severe sepsis. However, until now German guidelines for the diagnosis and therapy of severe sepsis did not exist. Therefore, the German Sepsis Society initiated the development of guidelines which are based on international recommendations by the International Sepsis Forum (ISF) and the Surviving Sepsis Campaign (SSC) and take into account the structure and organization of the German health care system. Priority was given to the following guideline topics: a) diagnosis, b) prevention, c) causative therapy, d) supportive therapy, e) adjunctive therapy. The guidelines development process was carefully planned and strictly adhered to the requirements of the Working Group of Scientific Medical Societies (AWMF).