Distribution of estrogen-concentrating, neurophysin-containing magnocellular neurons in the rat hypothalamus as demonstrated by a technique combining steroid autoradiography and immunohistology in the same tissue.
Distribution of estrogen-concentrating, neurophysin-containing magnocellular neurons in the rat hypothalamus as demonstrated by a technique combining steroid autoradiography and immunohistology in the same tissue.
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通过在同一组织中结合类固醇放射自显影和免疫组织学的技术证实了大鼠下丘脑中富含雌激素、含有神经素的大细胞神经元的分布。
DOI：
10.1159/000123195
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发表时间：
1981
影响因子：
4.1
通讯作者：
Pfaff,DW
中科院分区：
文献类型：
--
作者：
Rhodes,CH;Morrell,JI;Pfaff,DW
雌激素浓缩细胞在大鼠大脑中的分布，如含有催产素、抗利尿激素及其相关神经素的细胞的分布，先前已被详细描述过。本报告描述了在大鼠下丘脑细胞中，通过类固醇放射自显影和免疫组织学同时定位[Η]雌二醇。在大鼠中，含有神经physin的细胞存在于三个主要核——视上核、室旁核（PVN）和前联合核——以及一些副核和下丘脑前部的单个细胞中。在这些细胞中，只有PVN有相当数量的细胞既浓缩雌二醇又含有神经physin。在PVN内，这些细胞主要分布于后亚核。
The distribution of estrogen-concentrating cells in the rat brain has been previously described in detail as has the distribution of cells containing oxytocin, vasopressin, and their associated neurophysins. This report describes the simultaneous localization of [Η]estradiol by steroid autoradiography and neurophysin by immunohistology in cells in the rat hypothalamus. In the rat, neurophysin-containing cells were found in three major nuclei – the supraoptic nucleus, the paraventricular nucleus (PVN) and the anterior commissural nucleus – as well as in a number of accessory nuclei and as individual cells in the anterior hypothalamic area. Of these, only the PVN has appreciable numbers of cells which both concentrate estradiol and contain neurophysin. Within the PVN these cells are found predominantly in the posterior subnucleus.