Adsorption of insulin onto infusion sets used in adult intensive care unit and neonatal care settings.
Adsorption of insulin onto infusion sets used in adult intensive care unit and neonatal care settings.
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DOI：
10.1016/j.diabres.2008.02.013
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发表时间：
2008-06-01
影响因子：
5.1
通讯作者：
Shulman, Rob
中科院分区：
文献类型：
--
作者：
Zahid, Najam;Taylor, Kevin M G;Shulman, Rob
简介：胰岛素吸附到输液设备上可能会影响血糖控制。方法：使用连续流动UV分析确定通过成人ICU和新生儿患者使用的管路输送过程中胰岛素浓度的变化。结果：胰岛素吸附取决于管路组成、尺寸和流速，新生儿聚氯乙烯管路在低流速下的吸附最高。结论：在持续胰岛素治疗中，我们应该考虑输液器的性质和流速。
INTRODUCTION: Insulin adsorption onto infusion equipment may affect glycaemic control.METHODS: The change in insulin concentration during delivery through tubing employed for adult ICU and neonatal patients was determined using continuous flow UV analysis.RESULTS: Insulin adsorption depended on tubing composition, dimensions and flow rate, being highest for neonatal polyvinylchloride tubing at low flow rates.CONCLUSION: In continuous insulin therapy, we should consider the nature of the infusion set and flow rate.