First total synthesis of 25(R)-ruscogenin-1-yl β-D-xylopyranosyl-(1→3)-[β-D-glucopyranosyl-(1→2)]-β-fucopyranoside, an ophiopogonis saponin from the tuber of Liriope muscari (Decne.)
First total synthesis of 25(R)-ruscogenin-1-yl β-D-xylopyranosyl-(1→3)-[β-D-glucopyranosyl-(1→2)]-β-fucopyranoside, an ophiopogonis saponin from the tuber of Liriope muscari (Decne.)
复制标题
DOI：
10.1016/s0040-4039(97)10536-6
复制
发表时间：
1998-01-29
影响因子：
1.8
通讯作者：
Hui, YZ
中科院分区：
文献类型：
--
作者：
Liu, MZ;Yu, B;Hui, YZ
首次全合成 25(R)-ruscogenin-1-yl beta-D-xylopyranosyl-(1-->3)-[beta-D-glucopyranosyl-(1-->)]-beta-D-fucopyranoside (1)，一种来自 Liriope muusrari (Decne.) 块茎的麦冬皂苷，具有强抗炎和免疫药理学活性。通过施密特的“逆过程”证明了高度受阻醇的糖基化。 (C) 1997 Elsevier Science Ltd. 保留所有权利。
The first total synthesis of 25(R)-ruscogenin-1-yl beta-D-xylopyranosyl-(1-->3)-[beta-D-glucopyranosyl-(1-->)]-beta-D-fucopyranoside (1), an Ophiopogonis saponin with strong anti-inflammatory and immunopharmacological activities from the tuber of Liriope musrari (Decne.), is described. The glycosylaton of a highly hindered alcohol by Schmidt's "inverse procedure" is demonstrated. (C) 1997 Elsevier Science Ltd. All rights reserved.