Fatigue in women with breast cancer receiving radiation therapy
Fatigue in women with breast cancer receiving radiation therapy
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DOI：
10.1097/00002820-199804000-00006
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发表时间：
1998-04-01
期刊：
影响因子：
2.6
通讯作者：
Bubela, W
中科院分区：
文献类型：
--
作者：
Irvine, DM;Vincent, L;Bubela, W
疲劳是接受癌症治疗的个人的常见症状。缺乏严格的研究调查临床过程？放疗过程中疲劳的预后。76例接受外照射治疗的乳腺癌患者从治疗开始到治疗后6个月进行了纵向随访。疲劳在治疗过程中显著增加，rv在治疗的最后一周达到最高，并在治疗后3个月恢复到治疗前水平。疲劳不受患者年龄、疾病分期、手术时间、体重和确诊时间长短的影响。疲劳与症状困扰、心理困扰和自我报告的疲劳缓解策略显著相关。最常见的自我缓解策略是“坐”和“睡”。“疲劳对患者的生活质量产生了负面影响。治疗结束时，生活质量明显受损，改善？治疗后3个月和6个月的疗效。放射治疗的第二周至最后一周是针对疲劳管理进行干预的关键时期。伴随症状的改善是一种可能有帮助的支持性方法。患者报告称，停止活动和增加休息的自助策略是成功的。
Fatigue is a common complaint of individuals receiving treatment for cancer. There is a dearth of rigorous research investigating the clinical course ?prognosis of fatigue over-the course of radiation therapy. Seventy six patients with breast cancer receiving external radiation therapy were followed longitudinally from the onset of treatment to 6 months post-treatment. Fatigue significantly increased over-the course of treatment, rv as highest at the last week of treatment and returned to pretreatment levels by 3 months after treatment. Fatigue was not influenced by the patient's age, stage of disease, rime since surgery, weight, and length of time since diagnosis. Fatigue was significantly related to symptom distress, psychologic distress, and self-reported fatigue relief strategies. The most frequently reported self-reliefs strategies were "sit" and "sleep." Fatigue had a negative impact on the patient's quality of life. Impairment in quality of life was evident by the end of treatment, with improve?ment by 3 and 6 months after treatment. The second week through to the last week of radiation therapy are critical times to target interventions for the management of fatigue. The amelioration of concomitant symptoms is a supportive approach that might be helpful. Self-help strategies focusing on the cessation of activity and increasing rest were reported as successful by patients.