Variability in sleep bruxism activity over time
Variability in sleep bruxism activity over time
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DOI：
10.1046/j.1365-2869.2001.00261.x
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发表时间：
2001-09-01
影响因子：
4.4
通讯作者：
Montplaisir, JY
中科院分区：
文献类型：
--
作者：
Lavigne, GJ;Guitard, F;Montplaisir, JY
睡眠磨牙症（SB）是一种与下颌运动和牙齿研磨相关的口腔活动。睡眠磨牙症被认为是高度可变的，随着时间的推移，与科目显示在一些晚上没有活动和其他激烈的活动。评估个体患者的SB变异性对于旨在评估SB管理策略疗效的临床试验是必要的。本研究分析了9例中重度SB患者随时间推移的SB夜间变异性。不包括第一晚的习惯，共分析了37个夜晚，每个受试者的范围为2-8个夜晚。第一次和最后一次记录之间的间隔为2个月至7.5年。结果为每小时SB发作次数、每小时SB爆发次数和伴有磨音的SB发作次数。使用标准差（SD）和变异系数评价了三种SB orthogonal结局的受试者内变异性。为了验证受试者随时间的诊断，将orbital结局的值与标准研究诊断截止值进行比较：（1）每小时SB发作次数>4，（2）每小时SB爆发次数>25，（3）每晚噪音SB发作次数>1（Lavigne et al. 1996）。9名受试者的平均变异系数为25.3%（SB发作/小时）、30.4%（SB爆发/小时）和53.5%（噪声发作）。线性回归表明，SB发作的数量每小时的阶段I和2解释了很大比例的变异性。每例受试者的SB诊断随时间推移保持不变：37个晚上中有35个晚上符合标准I和2，而每晚都存在研磨。这些结果表明，虽然SB诊断在中度至重度睡眠磨牙者中随着时间的推移保持相对恒定，但个体差异在某些SB患者中可能很重要。
Sleep bruxism (SB) is an oral activity associated with jaw movements and tooth grinding. Sleep bruxism is believed to be highly variable over time, with subjects showing no activity on some nights and intense activity on others. Assessment of SB variability in individual patients is necessary for clinical trials designed to estimate the efficacy of SB management strategies. The present study analysed SB night-to-night variability over time in nine moderate to severe SB patients. Excluding the first night for habituation, a total of 37 nights were analysed, with a range of 2-8 nights per subject. The interval between the first and the last recording was between 2 months and 7.5 years. The outcomes were the number of SB episodes per hour, number of SB bursts per hour and number of SB episodes with grinding noise. The within subject variability of the three SB oromotor outcomes was evaluated using standard deviation (SD) and coefficient of variation. To verify the diagnosis of subjects over time, the values of the oromotor outcomes were compared with a standard research diagnostic cut-off: (1) Number of SB episodes per hour >4, (2) Number of SB bursts per hour >25, (3) Number of SB episodes with noise per night >1 (Lavigne et al. 1996). The mean coefficient of variation for the nine subjects was 25.3% for SB episodes per hour, 30.4% for SB bursts per hour and 53.5% for episodes with noise. Linear regression showed that the number of SB episodes per hour of stages I and 2 explains a large proportion of the variability. The SB diagnosis remained constant over time for every subject: 35 nights over 37 respected criteria I and 2, while grinding was present every night. These results indicate that while the SB diagnostic remains relatively constant over time in moderate to severe sleep bruxers, individual variability could be important in some SB patients.