THE FLUID CONTENT OF THE HUMAN INTERVERTEBRAL-DISK - COMPARISON BETWEEN FLUID CONTENT AND SWELLING PRESSURE PROFILES OF DISKS REMOVED AT SURGERY AND THOSE TAKEN POSTMORTEM
THE FLUID CONTENT OF THE HUMAN INTERVERTEBRAL-DISK - COMPARISON BETWEEN FLUID CONTENT AND SWELLING PRESSURE PROFILES OF DISKS REMOVED AT SURGERY AND THOSE TAKEN POSTMORTEM
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DOI：
10.1097/00007632-199204000-00006
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发表时间：
1992-04-01
期刊：
影响因子：
3
通讯作者：
MENAGE, J
中科院分区：
文献类型：
--
作者：
JOHNSTONE, B;URBAN, JPG;MENAGE, J
椎间盘的流体含量，决定其机械反应和生物学行为，随外部负荷而变化。 由于死亡后椎间盘上的负荷会发生变化，因此测量了尸检时采集的人类椎间盘的液体含量和膨胀压力曲线，并与手术过程中取出的椎间盘进行了比较。 一般来说，手术时取出的椎间盘与尸检时取出的椎间盘相比，髓核中的液体含量较低，外环中的液体含量较高。 在手术切除的椎间盘中，髓核的膨胀压力高于纤维环的膨胀压力，而在尸检椎间盘中，膨胀压力曲线是平坦的。 这些变化被认为是死后负荷变化的结果，并可能影响椎间盘体外力学测试的结果。
The fluid content of the disc, which governs its mechanical response and biological behavior, varies with external load. Because load on the disc changes after death, the fluid content and swelling pressure profiles of human discs taken at autopsy were measured, and compared with discs removed during surgical procedures. In general, discs taken at surgery had a lower fluid content in the nucleus and a higher fluid content in the outer anulus than discs removed at autopsy. In discs removed at surgery, the swelling pressure of the nucleus was higher than that of the anulus, whereas in autopsy discs the swelling pressure profile was flat. These changes are thought to result from changes in load after death, and could influence the results of in vitro mechanical tests on the disc.