THE DEVELOPMENT AND REPERTOIRE OF B-1 CELLS (CD5 B-CELLS)

THE DEVELOPMENT AND REPERTOIRE OF B-1 CELLS (CD5 B-CELLS)
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DOI:
10.1016/0167-5699(91)90136-h
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发表时间:
1991-11-01
期刊:
IMMUNOLOGY TODAY
影响因子:
--
通讯作者:
KANTOR, AB
KANTOR, AB
中科院分区:
其他
文献类型:
--
作者:
KANTOR, AB

文献摘要

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相似文献

小鼠和人类B细胞的一小部分产生大部分血清免疫球蛋白,包括许多常见的自身反应性抗体,并导致大多数B细胞慢性淋巴细胞白血病。最近一次令人兴奋的会议 * 集中讨论了这些细胞的发育、功能和谱系分类。召开会议讨论“CD 5 B细胞”,但以讨论“B-1细胞”结束(见参考文献1)。
A small subset of mouse and human B cells produces much of the serum immunoglobulin, including many common autoreactive antibodies, and accounts for most cases of B-cell chronic lymphocytic leukemia. An exciting recent conference* focused on the development, repertoire and lineage classification of these cells. The meeting was convened for a discussion of 'CD5 B cells' but ended with a discussion of 'B-1 cells' (see Ref. 1).