Monte Carlo characterization of a new Yb-169 high dose rate source for brachytherapy application
Monte Carlo characterization of a new Yb-169 high dose rate source for brachytherapy application
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DOI：
10.1118/1.3301607
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发表时间：
2010-03-01
期刊：
影响因子：
3.8
通讯作者：
Munro, John J., III
中科院分区：
文献类型：
--
作者：
Cazeca, Mario J.;Medich, David C.;Munro, John J., III
研究方法：蒙特卡罗模拟使用MCNP 5 F6能量沉积计数器放置在Yb-169源周围，在不同的径向距离，在空气真空和水的环境。计算基于半径为50 cm的球形水模。从模拟的输出被转换成径向剂量率分布在极坐标周围的近距离治疗source.Results：从蒙特卡罗模拟的结果被用来计算AAPM任务组43剂量学参数：各向异性函数，径向剂量函数，空气比释动能强度，剂量率常数。结果表明，剂量率常数为1.12 +/- 0.04 cGy h（-1）U-1，径向距离为0.5-10 cm，极角为0度-180度时，各向异性函数范围为0.44 - 1.00。来自Yb-169 HDR源M42型的数据显示，该源与Yb-169的另一个源4140型相比，已经被批准用于近距离放射治疗
Methods: Monte Carlo simulations were performed using the MCNP5 F6 energy deposition tallies placed around the Yb-169 source at different radial distances in both air-vacuum and water environments. The calculations were based on a spherical water phantom with a radius of 50 cm. The output from the simulations was converted into radial dose rate distribution in polar coordinates surrounding the brachytherapy source.Results: The results from Monte Carlo simulations were used to calculate the AAPM Task Group 43 dosimetric parameters: Anisotropy function, radial dose function, air kerma strength, and dose rate constant. The results indicate a dose rate constant of 1.12 +/- 0.04 cGy h(-1) U-1, anisotropy function ranging from 0.44 to 1.00 for radial distances of 0.5-10 cm and polar angles of 0 degrees-180 degrees.Conclusions: The data from the Yb-169 HDR source, Model M42, presented in this study show that this source compares favorably with another source of Yb-169, Model 4140, already approved for brachytherapy treatment.