SIGNIFICANCE PROBABILITY MAPPING - AN AID IN THE TOPOGRAPHIC ANALYSIS OF BRAIN ELECTRICAL-ACTIVITY

SIGNIFICANCE PROBABILITY MAPPING - AN AID IN THE TOPOGRAPHIC ANALYSIS OF BRAIN ELECTRICAL-ACTIVITY
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DOI:
10.1016/0013-4694(81)90221-2
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发表时间:
1981-01-01
期刊:
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子:
--
通讯作者:
BURCHFIEL, JL
BURCHFIEL, JL
中科院分区:
其他
文献类型:
--
作者:
DUFFY, FH;BARTELS, PH;BURCHFIEL, JL

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本文讨论了显著性概率图(SPM)在脑肿瘤患者、阅读障碍男孩和对照组的脑电地形图和视觉诱发电位(VEP)地形图分析中的应用。当肿瘤患者的VEP地形图显示为与参考平均值的标准差时,比通过检查基础原始数据正确识别更多的受试者。当听演讲或音乐时获得的EEG α活动的地形图通过t统计与静息α活动的图进行比较时,推测由演讲或音乐激活的皮层区域被描绘出来。不同的区域被定义在阅读障碍的男孩和控制。SPM可能被证明是有价值的正常和异常的功能在其他临床情况下的区域定位。
The application of significance probability mapping (SPM) to the analysis of topographic maps of spectral analyzed EEG and visual evoked potential (VEP) activity from patients with brain tumors, boys with dyslexia and control subjects, is discussed. When the VEP topographic plots of tumor patients were displayed as number of standard deviations from a reference mean, more subjects were correctly identified than by inspection of the underlying raw data. When topographic plots of EEG alpha activity obtained while listening to speech or music were compared by t statistic to plots of resting alpha activity, regions of cortex presumably activated by speech or music were delineated. Different regions were defined in dyslexic boys and controls. SPM may prove valuable in the regional localization of normal and abnormal functions in other clinical situations.