EFFERENT SYMPATHETIC NERVOUS CONTROL OF RECTAL MOTILITY IN THE CAT
EFFERENT SYMPATHETIC NERVOUS CONTROL OF RECTAL MOTILITY IN THE CAT
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DOI：
10.1111/j.1748-1716.1984.tb07462.x
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发表时间：
1984-01-01
期刊：
影响因子：
--
通讯作者：
HULTEN, L
中科院分区：
文献类型：
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作者：
HEDLUND, H;FASTH, S;HULTEN, L
在麻醉猫上研究了交感神经对直肠运动的控制。交感神经的分离，即，腹下神经和腰结肠神经，以及α-肾上腺素能阻滞降低直肠张力，表明这些神经是紧张性活动的。高强度的神经传出电刺激引起立即和持续的收缩，该收缩在酚妥拉明后被抑制，但不受六烃季铵的影响，这表明直接的α-对直肠平滑肌的肾上腺素能作用。然而，当主要直肠张力高时，β-观察到不受六甲铵影响的肾上腺素能抑制反应。腹下神经似乎将胆碱能兴奋性纤维传递到直肠。交感神经以类似于肛门内括约肌的神经控制的方式整合在直肠运动的神经调节中。
The sympathetic nervous control of rectal mobility was studied in anesthetized cats. Division of the sympathetic nerves, i.e., the hypogastric nerves and the lumbar colonic nerves, and .alpha.-adrenergic blockade reduced rectal tone, indicating that these nerves are tonically active. Efferent electrical stimulation of the nerves at high intensities caused an immediate and sustained contraction which was inhibited after phentolamine but unaffected by hexamethonium suggesting a direct .alpha.-adrenergic effect on the rectal smooth muscle. However when prevailing rectal tone was high, .beta.-adrenergic inhibitory responses unaffected by hexamethonium were observed. The hypogastric nerves seem to convey cholinergic excitatory fibers to the rectum. The sympathetic nerves are integrated in the nervous regulation of rectal motility in a fashion similar to the nervous control of the internal anal sphincter.