Macular lesions associated with retinitis pigmentosa.
Macular lesions associated with retinitis pigmentosa.
复制标题
与色素性视网膜炎相关的黄斑病变。
DOI：
--
复制
发表时间：
1977
期刊：
影响因子：
--
通讯作者：
J. Maggiano
中科院分区：
文献类型：
--
作者：
G. Fishman;M. Fishman;J. Maggiano
在31例视网膜色素变性患者中，18例（58%）在双眼黄斑内有视网膜色素上皮病变。31例患者中有6例（19%）显示黄斑囊肿或裂孔（5例双侧，1例单侧），而无中心凹周围毛细血管渗漏的血管造影证据，而7例患者（23%）双眼黄斑囊肿伴荧光素血管造影明显的黄斑囊样水肿。我们认为黄斑囊肿或裂孔是由于玻璃体视网膜界面的改变，如玻璃体牵拉和视网膜前膜。其他病理序列也可能是原因，例如视网膜毛细血管通透性的内在增加。
Of 31 patients with retinitis pigmentosa, 18 (58%) had lesions of the retinal pigmentary epithelium within the maculae of both eyes. Six of the 31 patients (19%) showed macular cysts or holes (five bilateral, one unilateral) without angiographic evidence of leakage from perifoveal capillaries, while seven patients (23%) had macular cysts in both eyes associated with cystoid macular edema evident by fluorescein angiography. We believe that the macular cysts or holes were caused by changes at the vitreoretinal interface, eg, vitreous traction and preretinal membranes. Other pathologic sequences may also be responsible, such as an intrinsic increase in the permeability of retinal capillaries.