Net costs of dementia by disease stage
Net costs of dementia by disease stage
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DOI：
10.1111/j.1600-0447.2011.01741.x
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发表时间：
2011-11-01
影响因子：
6.7
通讯作者：
Koenig, H. -H.
中科院分区：
文献类型：
--
作者：
Leicht, H.;Heinrich, S.;Koenig, H. -H.
目的：从社会角度估算痴呆严重程度的净成本，包括正式和非正式护理成本的详细评估。方法：在一项横断面研究中，对176名痴呆患者和173名匹配的非痴呆对照受试者的疾病成本进行了分析。通过问卷调查的方式对医疗资源使用和费用进行了回溯性评估。将痴呆患者分为3个疾病阶段，应用线性回归模型按病情严重程度估算痴呆的净成本。结果：按阶段划分的痴呆年净成本分别约为(SIC)15000(轻度)、(SIC)32000(中度)和(SIC)42000(重度)，分别为-21450美元、45760美元和60060美元。在疾病阶段，护理费用约占总费用的四分之三，其中一半来自非正式护理。在使用不同护理评估方法的敏感性分析中，总成本降低或增加了20%以上。结论：在痴呆症的不同阶段，净费用增加了一倍以上。非正规护理在护理费用中占相当大的份额，非正规护理的估值方法对疾病成本估算有很大影响。
Objective: To estimate net costs of dementia by degree of severity from a societal perspective, including a detailed assessment of costs of formal and informal nursing care.Method: In a cross-sectional study, costs of illness were analysed in 176 dementia patients and 173 matched non-demented control subjects. Healthcare resource use and costs were assessed retrospectively by means of a questionnaire. Dementia patients were classified into three disease stages, and linear regression models were applied to estimate net costs of dementia by degree of severity.Results: Annual net costs of dementia by stage were approximately (sic)15 000 (mild), (sic)32 000 (moderate) and (sic)42 000 (severe), corresponding to US-$21 450, 45 760 and 60 060 respectively. Across disease stages, nursing care accounted for approximately three-quarters of total costs, of which half resulted from informal care. In sensitivity analyses using different valuation methods for nursing care, total costs decreased or increased by more than 20%. Conclusion: Net costs more than double across stages of dementia. Informal care accounts for a considerable share of nursing care costs, and the approach to valuation of informal care has a large impact on cost-of-illness estimates.