A method to synchronize signals from multiple patient monitoring devices through a single input channel for inclusion in list-mode acquisitions
A method to synchronize signals from multiple patient monitoring devices through a single input channel for inclusion in list-mode acquisitions
复制标题
DOI：
10.1118/1.4828844
复制
发表时间：
2013-12-01
期刊：
影响因子：
3.8
通讯作者：
King, Michael A.
中科院分区：
文献类型：
--
作者：
O'Connor, J. Michael;Pretorius, P. Hendrik;King, Michael A.
目的：本技术笔记记录了作者开发的一种方法，该方法用于组合信号以使患者监护设备与第二生理信号同步，以包括在列表模式采集中。我们的具体应用需要通过将跟踪输入与心电输入多路传输来使外部患者运动跟踪系统与医学成像系统同步。作者认为他们的方法可以适用于各种医学成像模式，包括单光子发射计算机断层扫描(SPECT)和正电子发射断层扫描(PET)。然后，该序列与用于心电选通的R波脉冲一起被记录在列表模式采集中。我们的脉冲序列的特定形式允许识别被同步的时间点，即使当脉冲序列的一部分由于与R波脉冲的碰撞而丢失时也是如此。这是通过更改我们用于将列表模式数据装入库中的软件来实现的，以识别我们脉冲序列的一部分。通过模拟两个信号的混合作为心率的函数以及在心脏周期中我们的脉冲序列与心脏信号混合的时间点，研究了能够可靠地检测我们的脉搏序列的心率的限制。结果：作者通过获取最近在17个临床研究案例中使用的SPECT投影，成功地实现了我们的MotionTracing系统的准确的时间同步。在我们的模拟分析中，作者确定，在心率高达125次/分钟(Bpm)的情况下，可以实现同步以补偿身体和呼吸运动。结论：列表模式采集与外部患者监测设备(如用于运动跟踪的设备)的同步可以使用一种简单的方法可靠地实现，该方法可以通过单个输入通道使用最小的外部硬件和软件修改来实现，同时仍然记录心脏门控信号。(C)2013年美国医学物理学家协会。
Purpose: This technical note documents a method that the authors developed for combining a signal to synchronize a patient-monitoring device with a second physiological signal for inclusion into listmode acquisition. Our specific application requires synchronizing an external patient motion-tracking system with a medical imaging system by multiplexing the tracking input with the ECG input. The authors believe that their methodology can be adapted for use in a variety of medical imaging modalities including single photon emission computed tomography (SPECT) and positron emission tomography (PET).Methods: The authors insert a unique pulse sequence into a single physiological input channel. This sequence is then recorded in the list-mode acquisition along with the R-wave pulse used for ECG gating. The specific form of our pulse sequence allows for recognition of the time point being synchronized even when portions of the pulse sequence are lost due to collisions with R-wave pulses. This was achieved by altering our software used in binning the list-mode data to recognize even a portion of our pulse sequence. Limitations on heart rates at which our pulse sequence could be reliably detected were investigated by simulating the mixing of the two signals as a function of heart rate and time point during the cardiac cycle at which our pulse sequence is mixed with the cardiac signal.Results: The authors have successfully achieved accurate temporal synchronization of our motiontracking system with acquisition of SPECT projections used in 17 recent clinical research cases. In our simulation analysis the authors determined that synchronization to enable compensation for body and respiratory motion could be achieved for heart rates up to 125 beats-per-minute (bpm).Conclusions: Synchronization of list-mode acquisition with external patient monitoring devices such as those employed in motion-tracking can reliably be achieved using a simple method that can be implemented usingminimal external hardware and software modification through a single input channel, while still recording cardiac gating signals. (c) 2013 American Association of Physicists in Medicine.