ADAPTIVE BONE-REMODELING THEORY APPLIED TO PROSTHETIC-DESIGN ANALYSIS
ADAPTIVE BONE-REMODELING THEORY APPLIED TO PROSTHETIC-DESIGN ANALYSIS
复制标题
DOI：
10.1016/0021-9290(87)90030-3
复制
发表时间：
1987-01-01
影响因子：
2.4
通讯作者：
SLOOFF, TJ
中科院分区：
文献类型：
--
作者：
HUISKES, R;WEINANS, H;SLOOFF, TJ
本文的主题是计算机模拟方法的发展和应用，以预测应力相关的适应性骨重建，按照“沃尔夫定律”。这些模型是基于有限元法（FEM）结合自适应骨重塑理论的数值公式。在自适应重塑模型中，应变能密度（SED）被用作反馈控制变量，以确定形状或骨密度适应替代功能要求，从而稳态SED分布被假定为重塑目标。这些模型用于研究髓内假体周围股骨皮质中“应力屏蔽”和骨吸收之间的关系，例如用于全髋关节置换术（THA）。结果表明，骨吸收的量主要取决于种植体的刚度和粘结特性。当吸收过程发生在骨膜表面而不是皮质内时，只要股骨柄具有足够的柔性，就可以获得稳态SED。
The subject of this article is the development and application of computer-simulation methods to predict stress-related adaptive bone remodeling, in accordance with ''Wolffs Law''. These models are based on the Finite Element Method (FEM) in combination with numerical formulations of adaptive bone-remodeling theories. In the adaptive remodeling models presented, the Strain Energy Density (SED) is used as a feed-back control variable to determine shape or bone density adaptations to alternative functional requirements, whereby homeostatic SED distribution is assumed as the remodeling objective. These models are applied to investigate the relation between ''stress shielding'' and bone resorption in the femoral cortex around intramedullary prostheses, such as used in Total Hip Arthroplasty (THA). It is shown that the amount of bone resorption depends mainly on the rigidity and the bonding characteristics of the implant. Homeostatic SED can be obtained when the resorption process occurs at the periosteal surface, rather than inside the cortex, provided that the stem is adequately flexible.