Actinobacillus pleuropneumoniae serovar 8 predominates in England and Wales
Actinobacillus pleuropneumoniae serovar 8 predominates in England and Wales
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DOI：
10.1136/vr.103820
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发表时间：
2016-09-17
影响因子：
2.2
通讯作者：
Langford, P. R.
中科院分区：
文献类型：
--
作者：
Li, Y.;Bosse, J. T.;Langford, P. R.
胸膜肺炎放线杆菌是胸膜肺炎的主要病因，胸膜肺炎是一种猪的急性或慢性肺部疾病，在全球养猪业中导致显著的发病率、死亡率和经济损失（Bossé等人，2002年; Gottschalk，2012年）。通过荚膜多糖的组成确定了15种已确立的细菌血清型（Gottschalk 2012），另一种血清型仅基于血清学提出（Sárközi等人2015）。确定血清型有助于深入了解A.例如，利用胸膜肺炎病毒，绘制疾病暴发地图，查明以前在各国未发现的血清型的引入，并协助配制疫苗。血清型患病率因国家和时间而异（Dubreuil等人，2000年; Gottschalk，2015年）。例如，目前血清型5和7在加拿大占主导地位（Gottschalk和Lacouture 2015），而直到20世纪90年代，血清型1（Gottschalk 2015）。在澳大利亚，血清型15高度流行（Turni等人，2014年），但在其他地方很少报告，尽管最近在加拿大（Gottschalk和Lacouture，2014年）和日本（Koyama等人，2007年）也可能发现。
Actinobacillus pleuropneumoniae is a major cause of pleuropneumonia, an acute or chronic lung disease of pigs that causes significant morbidity, mortality and economic losses in the worldwide pig industry (Bossé and others 2002, Gottschalk 2012). There are 15 established serovars of the bacterium determined by the composition of the capsular polysaccharide (Gottschalk 2012) with another proposed based on serology alone (Sárközi and others 2015). Determining the serovar allows insights into the epidemiology of A. pleuropneumoniae, for example, to map outbreaks of disease, to identify introductions of serovars not previously detected in countries and to assist in the formulation of bacterin vaccines. Serovar prevalence varies from country to country and with time (Dubreuil and others 2000, Gottschalk 2015). For example, currently serovars 5 and 7 dominate in Canada (Gottschalk and Lacouture 2015), whereas until the 1990s, it was serovar 1 (Gottschalk 2015). In Australia, serovar 15 is highly prevalent (Turni and others 2014) but is rarely reported elsewhere, although it has been recently found in Canada (Gottschalk and Lacouture 2014) and possibly also in Japan (Koyama and others 2007).