The Saskatchewan Pediatric Bone Mineral Accrual Study: Bone mineral acquisition during the growing years
The Saskatchewan Pediatric Bone Mineral Accrual Study: Bone mineral acquisition during the growing years
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DOI：
10.1055/s-2007-972713
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发表时间：
1997-07-01
影响因子：
2.5
通讯作者：
Bailey, DA
中科院分区：
文献类型：
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作者：
Bailey, DA
为了调查生长期儿童的骨矿物质增加，萨斯喀彻温省儿科骨矿物质增加研究于1991年启动。这项研究包括收集饮食和身体活动信息，沿着每6个月进行一次人体测量和成熟度测量，以及每年对全身、AP腰椎和股骨近端进行一次双能X射线骨吸收仪（DXA）骨扫描。这项研究已经完成了第6年，来自228名小学生的原始样本中的68名男性和72名女性仍然参与其中，为了研究临床上重要部位的骨矿物质如何与成熟相关，我们开发了AP腰椎、股骨颈和全身的身高和骨矿物质含量（BMC）的距离和速度生长曲线。在男孩和女孩中，超过35%的全身和AP脊柱骨矿物质和超过27%的股骨颈骨矿物质是在4岁青少年时期围绕峰值线性生长速度沉积的。这些值的临床意义可以通过考虑以下事实来理解，即在这4个青少年生长期内沉积的骨矿物质与大多数人在整个成年期内丢失的骨矿物质一样多。
To investigate bone mineral accretion in growing children, the Saskatchewan Pediatric Bone Mineral Accrual Study was initiated in 1991. The study involves the collection of dietary and physical activity information along with anthropometric growth and maturity measurements every 6 months and dual-energy X-ray absorptiometer (DXA) bone scans of the whole body, AP lumbar spine and proximal femur taken annually, The study has now finished its 6th year and 68 males and 72 females from an original sample of 228 elementary schoolchildren are still involved, To investigate how bone mineral at clinically important sites proceeds in relation to maturation we developed distance and velocity growth curves for height and bone mineral content (BMC) for the AP lumbar spine, the femoral neck and the whole body, In both boys and girls, over 35% of total body and AP spine bone mineral and over 27% of the bone mineral at the femoral neck was laid down during the 4-year adolescent period surrounding peak linear growth velocity. The clinical significance of these values can be appreciated by consideration of the fact that as much bone mineral will be laid down during these 4 adolescent growing years as most people will lose during all of adult life.