The association of education with long-term weight change in the EPIC-PANACEA cohort
The association of education with long-term weight change in the EPIC-PANACEA cohort
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DOI：
10.1038/ejcn.2012.55
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发表时间：
2012-08-01
影响因子：
4.7
通讯作者：
Peeters, P. H. M.
中科院分区：
文献类型：
--
作者：
Rohrmann, S.;Steinbrecher, A.;Peeters, P. H. M.
背景/目标：从横截面来看，受教育程度与肥胖患病率密切相关，但这种关联与成年后体重变化的关系不太明确。本研究的目的是在欧洲癌症与营养前瞻性调查 (EPIC) 中探讨成年期间受教育程度与体重变化之间的关联。 主题/方法：EPIC 是一项队列研究，有 361 467 名参与者参与，随访期长达 10 年。教育程度按照最高学历（小学或以下、职业中等教育、其他中等教育和大学）进行分类。使用多变量混合效应线性回归模型来研究教育与 20 岁时体重（自我报告）、20 岁时体重与招募时测量体重之间的年度变化以及随访期间体重的年度变化的关系。 结果：较高的教育程度与平均 20 岁时较低的体重指数 (BMI) 和招募前体重增长的较低程度相关（最高教育程度与最低教育程度 男性：每年 -60 克（95% 置信区间 (CI) -80；-40），女性每年 -110 克（95% CI -130；-80））。尽管在招募后的随访中，所有教育水平的人体重均有所增加，但具有大学学位的男性和女性的体重增长最低（高教育与低教育分别为每年 -120 克（95% CI -150; -90）和每年 -70 克（95% CI -90; -60））。 终生，这可能会影响受教育程度较低的人与肥胖相关的慢性病风险。
BACKGROUND/OBJECTIVES: Cross-sectionally, educational attainment is strongly associated with the prevalence of obesity, but this association is less clear for weight change during adult life. The objective of this study is to examine the association between educational attainment and weight change during adult life in the European Prospective Investigation into Cancer and Nutrition (EPIC).SUBJECTS/METHODS: EPIC is a cohort study with 361 467 participants and up to 10 years of follow-up. Educational attainment was categorized according to the highest obtained school level (primary school or less, vocational secondary training, other secondary education and university). Multivariate mixed-effects linear regression models were used to study education in relation to weight at age 20 years (self-reported), to annual change in weight between age 20 years and measured weight at recruitment, and to annual change in weight during follow-up time.RESULTS: Higher educational attainment was associated with on average a lower body mass index (BMI) at age 20 years and a lower increase in weight up to recruitment (highest vs lowest educational attainment in men: -60 g per year (95% confidence interval (CI) -80; -40), women -110 g per year (95% CI -130; -80)). Although during follow-up after recruitment an increase in body weight was observed in all educational levels, gain was lowest in men and women with a university degree (high vs low education -120 g per year (95% CI -150; -90) and -70 g per year (95% CI -90; -60), respectively).CONCLUSIONS: Existing differences in BMI between higher and lower educated individuals at early adulthood became more pronounced during lifetime, which possibly impacts on obesity-related chronic disease risk in persons with lower educational attainment.