Cobalt-catalyzed intermolecular stereoselective bisbenzylation of alkynes
Cobalt-catalyzed intermolecular stereoselective bisbenzylation of alkynes
复制标题
DOI：
10.1016/j.tetlet.2015.02.101
复制
发表时间：
2015-03-25
影响因子：
1.8
通讯作者：
Takaki, Ken
中科院分区：
文献类型：
--
作者：
Komeyama, Kimihiro;Asakura, Ryota;Takaki, Ken
在锰还原剂存在下，CoBr2/P(OMe)Ph-2是一种有效的分子间双苄基化催化体系。转化可以在温和的条件下进行，生成立体控制的顺式-1,2-双苄基烯烃，产率高。(C) 2015年Elsevier Ltd.出版
CoBr2/P(OMe)Ph-2 is found to be an effective catalyst-system for intermolecular bisbenzylation of allcynes with various benzyl bromides in the presence of manganese reductant. The transformation can be carried out under mild conditions, giving rise to stereocontrolled cis-1,2-bisbenzylated alkenes in good yields. (C) 2015 Published by Elsevier Ltd.