Outcome of West Nile fever in older adults
Outcome of West Nile fever in older adults
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DOI：
10.1046/j.1532-5415.2002.505402.x
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发表时间：
2002-11-01
影响因子：
6.3
通讯作者：
Chowers, MY
中科院分区：
文献类型：
--
作者：
Berner, YN;Lang, R;Chowers, MY
目的：探讨临床表现和认知改变对老年西尼罗热（WNF）患者出院后预后的影响。设计：回顾性队列分析。环境：梅尔医院位于以色列中部沙龙地区。参与者：32名65岁及以上患者在WNF爆发期间住院。测量：回顾性分析所有患者的病历，特别强调他们的认知和功能状态。3个月后对出院时功能下降的患者进行随访检查。结果：是意识的变化而不是认知的变化预测了结果。死亡率为22% (7/32)；所有死亡个案年龄均在78岁或以上。同样，功能衰退和残余损伤只出现在年龄较大的年龄组（大于或等于75岁）。88%的幸存者恢复了发病前的功能。与其他病毒感染相比，受试者的慢性疾病对结果没有影响。结论：在老年人中，WNF具有高死亡率，但对幸存者有利。
OBJECTIVES: To determine the effect of clinical presentation and cognitive changes on the postdischarge outcome in older adult patients with West Nile fever (WNF).DESIGN: Retrospective, cohort analysis.SETTING: Meir Hospital located in the center of Israel in the Sharon region.PARTICIPANTS: Thirty-two patients aged 65 and older hospitalized during a WNF outbreak.MEASUREMENTS: All patients' charts were analyzed retrospectively with special emphasis on their cognitive and functional state. A follow-up examination of patients with functional decline at discharge was performed after 3 months.RESULTS: A change in consciousness, rather than in cognition, predicted the outcome. The death rate was 22% (7/32); all fatal cases were aged 78 and older. Similarly, the functional decline and residual damage appeared only in the older age group (greater than or equal to75). Eighty-eight percent of the survivors returned to their premorbid function. In contrast to other viral infections, chronic conditions in the subjects had no effect on the outcome.CONCLUSIONS: In older adults, WNF carries a high death rate, but the outcome is favorable for the survivors.