Psychopharmacology and aggression. I: A meta-analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD
Psychopharmacology and aggression. I: A meta-analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD
复制标题
DOI：
10.1097/00004583-200203000-00004
复制
发表时间：
2002-03-01
影响因子：
13.3
通讯作者：
Melloni, RH
中科院分区：
文献类型：
--
作者：
Connor, DF;Glatt, SJ;Melloni, RH
目的：通过荟萃分析确定兴奋剂对注意力缺陷/多动障碍 (ADHD) 儿童的显性和隐性攻击相关行为的影响大小，以及兴奋剂对 ADHD 核心症状的影响。方法：回顾 1970 年至 2001 年的文献，发现有 28 项研究符合荟萃分析的纳入/排除标准。这些研究得出了 28 种公开攻击的独立影响和 7 种隐蔽攻击的独立影响。结果：ADHD 中公开攻击相关行为的总体加权平均效应大小为 0.84，隐性攻击相关行为的总体加权平均效应大小为 0.69。共病品行障碍与明显攻击行为的刺激效应大小减少有关。结论：对 ADHD 攻击相关行为的刺激作用与对 ADHD 核心症状的作用大小相似。
Objective: To determine by meta-analysis the effect size for stimulants on overt and covert aggression-related behaviors in children with attention-deficit/hyperactivity disorder (ADHD), separately from stimulant effects on the core symptoms of ADHD. Method: A review of the literature from 1970 to 2001 revealed 28 studies meeting inclusion/exclusion criteria for meta-analysis. These studies yielded 28 independent effects of overt aggression and 7 independent effects of covert aggression. Results: The overall weighted mean effect size was 0.84 for overt and 0.69 for covert aggression related behaviors in ADHD. Comorbid conduct disorder is associated with diminishing stimulant effect size for overt aggression. Conclusion: Stimulant effects for aggression-related behaviors in ADHD have effect sizes similar to those for the core symptoms of ADHD.