Dyspnea in interstitial lung disease.
Dyspnea in interstitial lung disease.
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DOI：
10.1097/spc.0b013e3282ff6336
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发表时间：
2008-06-01
影响因子：
2.1
通讯作者：
Pantilat, Steven Z
中科院分区：
文献类型：
--
作者：
Collard, Harold R;Pantilat, Steven Z
回顾目的：呼吸困难是间质性肺疾病的常见并发症，但对其原因和有效治疗知之甚少。这篇综述试图总结这一领域的现状。最近发现：呼吸困难在间质性肺疾病患者中几乎是一种普遍的发现，主要是由于神经力学异常。在这一人群中，有几个被充分研究的测量呼吸困难的指标，其严重程度与生活质量和生存有关。间质性肺疾病呼吸困难的管理仍然是一个挑战，没有经过证实的药物选择。肺部康复显示出治疗前景，积极治疗身体和精神合并症是很重要的。摘要：呼吸困难仍然是间质性肺疾病患者常见且难以治疗的症状。迫切需要更多的研究。
PURPOSE OF REVIEW: Dyspnea is a common complication of interstitial lung disease, yet little is known about its cause and effective management. This review attempts to summarize the current state of the art in this area.RECENT FINDINGS: Dyspnea is a near-universal finding in people with interstitial lung disease, predominantly due to neuromechanical abnormalities. Several well studied metrics exist for the measurement of dyspnea in this population, and its severity has been linked to quality of life and survival. The management of dyspnea in interstitial lung disease remains a challenge, with no proven pharmacological options. Pulmonary rehabilitation shows therapeutic promise, and aggressive treatment of physical and psychiatric comorbidities is important.SUMMARY: Dyspnea remains a common and difficult to treat symptom for people with interstitial lung disease. More research is sorely needed.