High Tuberculosis Strain Diversity Among New York City Public Housing Residents
High Tuberculosis Strain Diversity Among New York City Public Housing Residents
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DOI：
10.2105/ajph.2015.302910
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发表时间：
2016-03-01
影响因子：
12.7
通讯作者：
Ahuja, Shama D.
中科院分区：
文献类型：
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作者：
Dawson, Patrick;Perri, Bianca R.;Ahuja, Shama D.
目标.我们试图更好地了解结核病（TB）的流行病学纽约市住房管理局（NYCHA）的居民，在最近的结核病调查确定患者谁拥有相同的结核菌株。研究人群包括2001年至2009年期间确诊的所有纽约市结核病患者。诊断时患者地址确定为NYCHA住所。我们计算了结核病的发病率，回顾了结核菌株数据，并确定了与结核病聚集相关的因素。在2001年至2009年期间，纽约市的8953名结核病患者中，512人（6%）有NYCHA地址。在美国出生的人中，NYCHA居民的结核病发病率（6.0/100 000人）是非NYCHA居民（3.0/100 000人）的两倍。NYCHA的患者具有较高的结核菌株多样性。美国出生，年轻，和物质使用与结核病聚集在NYCHA个人与TB。NYCHA结核病患者的结核菌株多样性高并不意味着在居民中传播。这些发现说明，NYCHA较高的结核病发病率可能是由于其较高的浓度与已知的结核病危险因素的个人。
Objectives. We sought to better understand tuberculosis (TB) epidemiology among New York City Housing Authority (NYCHA) residents, after a recent TB investigation identified patients who had the same TB strain.Methods. The study population included all New York City patients with TB confirmed during 2001 through 2009. Patient address at diagnosis determined NYCHA residence. We calculated TB incidence, reviewed TB strain data, and identified factors associated with TB clustering.Results. During 2001 to 2009, of 8953 individuals in New York City with TB, 512 (6%) had a NYCHA address. Among the US-born, TB incidence among NYCHA residents (6.0/100 000 persons) was twice that among non-NYCHA residents (3.0/100 000 persons). Patients in NYCHA had high TB strain diversity. US birth, younger age, and substance use were associated with TB clustering among NYCHA individuals with TB.Conclusions. High TB strain diversity among residents of NYCHA with TB does not suggest transmission among residents. These findings illustrate that NYCHA's higher TB incidence is likely attributable to its higher concentration of individuals with known TB risk factors.