Lung Cells Grown on Cellulose Membrane Filters as an In Vitro Model of the Respiratory Epithelium
Lung Cells Grown on Cellulose Membrane Filters as an In Vitro Model of the Respiratory Epithelium
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在纤维素膜过滤器上生长的肺细胞作为呼吸道上皮的体外模型
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
T. Crocker
中科院分区：
文献类型：
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作者：
R. Rasmussen;T. Crocker
空气传播的物质大部分是通过首先接触呼吸道上皮的某个部分进入人体的。微粒和气体可通过溶解于细胞膜或胞饮作用穿过上皮细胞。不可溶颗粒可能被巨噬细胞和粘液纤毛清除机制吞噬和清除，但充满颗粒物质的巨噬细胞可能会在肺内停留较长时间，并成为其他细胞继续暴露于潜在毒素的来源。
Airborne agents enter the body for the most part by first contacting some part of the respiratory epithelium. Particulates and gases may cross the epithelium by solution in the cell membranes or pinocytosis. Insoluble particles may be engulfed and removed by macrophages and mucociliary clearance mechanisms, but macrophages engorged with particulate materials may remain in the lung for prolonged times and serve as a source for continued exposure of other cells to potential toxins.