P-element-induced mutation and quantitative variation in Drosophila melanogaster : lack of enhanced response to selection in lines derived from dysgenic crosses.
P-element-induced mutation and quantitative variation in Drosophila melanogaster : lack of enhanced response to selection in lines derived from dysgenic crosses.
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P元素诱导的黑腹果蝇突变和数量变异：对来自基因不良杂交的品系中的选择缺乏增强的反应。
DOI：
10.1017/s0016672300024332
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发表时间：
1988
影响因子：
1.5
通讯作者：
F. Nicholas
中科院分区：
文献类型：
--
作者：
A. Torkamanzehi;C. Moran;F. Nicholas
通过Harwich（P）和Canton-S（M）菌株的相互杂交，建立了基因失调和非基因失调的基础群体。每个杂交组合建立2个上、2个下选择系，对腹毛数进行10代选择。选择的强度是从每种性别的50个个体中选出10个。在选择条件下，比较了非基因型群体和非基因型群体的平均刚毛数、表型变异和遗传力。除了一个异常的非dysgenic下行线中发生的突变的大的影响，所有线路显示出类似的选择。这些结果与Mackay（1984，1985）报道的结果相反，在Mackay报道的结果中，与非劣基因系相比，劣基因系对选择的反应、表型变异和遗传力得到了显著增加。有一些迹象表明，在我们的异常的非dysgenic下线较高的反应是转座的结果。可能的解释发生的易位和发育不良的线来自nondysgenic杂交进行了讨论。
Dysgenic and non-dysgenic base populations were made by reciprocal crossing of Harwich (P) and Canton-S (M) strains. From each cross, two up and two down selection lines were established, with selection on abdominal bristle number for ten generations. The intensity of selection was 10 out of 50 individuals from each sex. Mean bristle number, phenotypic variation and heritabilities were compared between dysgenic and non-dysgenic populations under selection. Except for an anomalous non-dysgenic downline in which a mutation of large effect occurred, all lines showed similar responses to selection. These results contrast with the results reported by Mackay (1984, 1985) in which substantial increases were obtained for response to selection, phenotypic variation and heritability in the dysgenic compared to non-dysgenic lines. There are some indications that the higher response in our aberrant non-dysgenic downline is the result of transposition. Possible explanations for the occurrence of transposition and dysgenesis in the lines derived from nondysgenic crosses are discussed.
果蝇中的转座酶滴定：杂交发育不全 P-M 系统中的细胞型模型。
DOI：
10.1073/pnas.82.23.8119
发表时间：
1985
影响因子：
11.1
作者：
Simmons,MJ;Bucholz,LM
通讯作者：
Bucholz,LM