EXCITATION OF DORSAL-ROOT FIBERS IN SPINAL-CORD STIMULATION - A THEORETICAL-STUDY
EXCITATION OF DORSAL-ROOT FIBERS IN SPINAL-CORD STIMULATION - A THEORETICAL-STUDY
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DOI：
10.1109/10.237693
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发表时间：
1993-07-01
影响因子：
4.6
通讯作者：
BOOM, HBK
中科院分区：
文献类型：
--
作者：
STRUIJK, JJ;HOLSHEIMER, J;BOOM, HBK
在硬膜外脊髓刺激中，很可能不仅背柱纤维被激活，而且背根纤维也将被涉及。在这项调查中，体积导体模型的脊髓和背根纤维建模的电网络，包括纤维激发。研究了不同几何结构的纤维特性对脊髓背侧脑脊液层和电极结构对脊髓背侧柱纤维兴奋阈值的影响，并与脊髓背侧柱纤维的阈值进行了比较。本模拟研究的结果预测，除了众所周知的纤维直径的影响，背根纤维的曲率和这些纤维与脊髓轴之间的角度是其阈值的主要影响。由于这些影响，背根纤维的阈值刺激相对较低，相比背柱纤维。背根纤维的兴奋发生在纤维进入点附近。
In epidural spinal cord stimulation it is likely that not only dorsal column fibers are activated, but that dorsal root fibers will be involved as well. In this investigation a volume conductor model of the spinal cord was used and dorsal root fibers were modeled by an electrical network including fiber excitation. The effects of varying some geometrical fiber characteristics, as well as the influence of the dorsal cerebrospinal fluid layer and the electrode configuration on the threshold stimulus for their excitation, were assessed.The threshold values were compared with those of dorsal column fibers. The results of this modeling study predict that, besides the well known influence of fiber diameter, the curvature of the dorsal root fibers and the angle between these fibers and the spinal cord axis were of major influence on their threshold values. Because of these effects, threshold stimuli of dorsal root fibers were relatively low as compared to dorsal column fibers. Excitation of the dorsal root fibers occurred near the entry point of the fibers.