Effects of theta burst stimulation protocols on phosphene threshold
Effects of theta burst stimulation protocols on phosphene threshold
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DOI：
10.1016/j.clinph.2006.03.019
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发表时间：
2006-08-01
影响因子：
4.7
通讯作者：
Rothwell, John C.
中科院分区：
文献类型：
--
作者：
Franca, Michele;Koch, Giacomo;Rothwell, John C.
目的：我们研究了两种新开发的重复经颅磁刺激（rTMS）方法对枕叶皮层的影响：连续和间歇theta爆发刺激方法：在连续或间歇性θ波刺激前后，测量对单一TMS脉冲的光幻视阈值结果：在我们的队列中，cTBS使光幻视阈值平均增加10%。相反，iTBS，这短暂增加运动皮层兴奋性，没有效果的光幻视threshold.Conclusions：cTBS可以成功地应用于非运动区的皮层，但iTBS可能需要修改，以产生最大的effects.Significance：cTBS可能是一个新的有用too]的障碍，其特征是异常状态的活动的视觉皮层。(c)2006年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: We investigated the effects on occipital cortex, of two newly developed methods of repetitive transcranial magnetic stimulation (rTMS): continuous and intermittent theta burst stimulation (cTBS and iTBS), that lead to long lasting changes in excitability when applied over primary motor cortex.Methods: Phosphene threshold to a single TMS pulse was measured before and after application of either continuous or intermittent theta burst stimulation (cTBS/iTBS; 600 total pulses at 80% phosphene threshold).Results: In our cohort, cTBS increased phosphene threshold by an average of 10%. In contrast, iTBS, which transiently increases motor cortex excitability, had no effect on phosphene threshold.Conclusions: cTBS can be applied successfully to non-motor areas of cortex, but iTBS may need modification to produce maximal effects.Significance: cTBS maybe a new useful too] in disorders characterized by an abnormal state of activity of the visual cortex. (c) 2006 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.