FLUCTUATION DRIVEN RATCHETS - MOLECULAR MOTORS
FLUCTUATION DRIVEN RATCHETS - MOLECULAR MOTORS
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DOI：
10.1103/physrevlett.72.1766
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发表时间：
1994-03-14
影响因子：
8.6
通讯作者：
BIER, M
中科院分区：
文献类型：
--
作者：
ASTUMIAN, RD;BIER, M
研究了重阻尼布朗粒子在周期势场中受二分涨落扰动的运动。我们表明，即使净力总是为零，流动是由能量势垒的波动引起的，但只有在翻转时间大致在绝热调整时间之间的左侧和右侧的障碍。我们的模型的预测与Svoboda等人[Nature（伦敦）365，721-727（1993）]最近获得的关于单个驱动蛋白分子沿生物聚合物沿着移动的实验数据一致。
The motion of a heavily damped Brownian particle in a periodic potential subject to a dichotomously fluctuating perturbation is considered. We show that even if the net force is always zero, flow is induced by a fluctuation of the energy barrier, but only at flipping times roughly in between the adiabatic adjustment times on the left and right of the barrier. Predictions of our model are consistent with recent experimental data obtained by Svoboda et al. [Nature (London) 365, 721-727 (1993)] for a single kinesin molecule moving along a biopolymer.