Sensations of heaviness.
Sensations of heaviness.
复制标题
沉重的感觉。
DOI：
10.1093/brain/100.2.345
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发表时间：
1977
期刊：
影响因子：
--
通讯作者：
D. McCloskey
中科院分区：
文献类型：
--
作者：
S. Gandevia;D. McCloskey
我们研究了两组受试者对重量的感受； 8 名患有不同程度单侧“上运动神经元”无力但无感觉症状或体征的患者，以及 10 名志愿者的前臂和手部部分箭毒化过程中。在所有实验中，受试者将弱侧举起的参考重量与强侧的可变重量相匹配，以提供参考重量重量的客观指示。患者将装满水银的网球的重量或通过伸出食指举起的重量进行匹配。在偏瘫患者和用箭毒削弱的正常受试者中，当由削弱的一侧提起时，重量被判断为更重。在偏瘫患者和被箭毒削弱的受试者中，外周感觉信息将发出举起重物时所施加的力的信号；然而，两组受试者显然更依赖于收缩所付出的努力，而不是所达到的周围张力。我们在估计体重时部分依赖于运动神经元的传感命令的概念与霍姆斯对单侧小脑功能障碍患者的观察以及最近的生理实验一致。
We have studied the appreciation of heaviness in two groups of subjects; in 8 patients with varying degrees of unilateral 'upper motor neuron' weakness but without sensory symptoms or signs, and in 10 volunteers during partial curarization of the forearm and hand. In all experiments the subjects matched a reference weight lifted on the weak side with a variable weight on the strong side to provide an objective indication of the heaviness of the reference weight. Patients matched the weights of tennis balls filled with mercury or weights lifted by extending the index finger. Weights were judged as heavier when lifted by the weakened side both in the hemiparetic patients and in normal subjects weakened with curare. In both the hemiparetic patients and the subjects weakened with curare peripheral sensory information would signal the forces exerted in lifting the weight; however, both groups of subjects clearly placed more reliance on the effort that was being put into the contraction than on peripheral tensions achieved. The concept that we rely in part on a sensing command to the motoneurons when estimating weight agrees with observations by Holmes on patients with unilateral cerebellar dysfunction, and with recent physiological experiments.