Peripheral natural killer cytotoxicity and CD56posCD16pos cells increase during early pregnancy in women with a history of recurrent spontaneous abortion
Peripheral natural killer cytotoxicity and CD56posCD16pos cells increase during early pregnancy in women with a history of recurrent spontaneous abortion
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DOI：
10.1093/humrep/15.5.1163
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发表时间：
2000-05-01
影响因子：
6.1
通讯作者：
Joosten, I
中科院分区：
文献类型：
--
作者：
Emmer, PM;Nelen, WLDM;Joosten, I
出于诊断目的，我们评估了外周自然杀伤（NK）细胞的细胞毒性以及NK和T细胞数量，以评估其对复发性自然流产（RSA）的预测价值。共有43名随后怀孕的妇女，37名健康对照和39名成功参与体外受精（IVF）程序的妇女被纳入研究。我们发现，在怀孕前，RSA妇女和对照组之间的NK细胞毒性水平和单个CD56（pos）和双CD56（pos）CD16（pos）细胞的数量是相似的。但值得注意的是，在RSA组中，
For diagnostic purposes we assessed peripheral natural killer (NK) cell cytotoxicity and NK and T cell numbers to assess their putative predictive value in recurrent spontaneous abortion (RSA). A total of 43 women with subsequent pregnancy, 37 healthy controls and 39 women successfully partaking in an in-vitro fertilization (IVF) procedure, were included in the study. We show that before pregnancy, levels of NK cytotoxicity and numbers of both single CD56(pos) and double CD56(pos)CD16(pos) cells were similar between RSA women and controls. But notably, within the RSA group, NK cell numbers of