Longitudinal study of the effects of maternal smoking on pulmonary function in children.
Longitudinal study of the effects of maternal smoking on pulmonary function in children.
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DOI：
10.1097/00006254-198404000-00004
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发表时间：
1983-09
期刊：
影响因子：
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通讯作者：
I. Tager;S. Weiss;A. Muñoz;B. Rosner;F. Speizer
中科院分区：
文献类型：
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作者：
I. Tager;S. Weiss;A. Muñoz;B. Rosner;F. Speizer
我们研究了母亲吸烟对一组儿童和青少年肺功能的影响，前瞻性观察了7年。一项多变量分析显示，在校正了儿童或青少年的一秒钟用力呼气量（FEV1）、年龄、身高、身高变化和吸烟情况后，母亲吸烟显著降低了FEV1的预期平均年增长率（P = 0.015）。根据这一分析，据估计，如果两名儿童的初始FEV1、年龄、身高、身高增长和个人吸烟史相同，但其中一名儿童的母亲终生吸烟，而另一名儿童的母亲没有吸烟，则暴露儿童与未暴露儿童的FEV1随时间变化的差异约为28，一年、两年和五年后分别为51毫升、101毫升，即比预期增加量分别减少10.7%、9.5%和7.0%。这些结果表明，被动暴露于母亲的香烟烟雾可能有重要的影响，肺功能的发展在儿童。
We investigated the effects of maternal cigarette smoking on pulmonary function in a cohort of children and adolescents observed prospectively for seven years. A multivariate analysis revealed that after correction for previous forced expiratory volume in one second (FEV1), age, height, change in height, and cigarette smoking in the child, or adolescent, maternal cigarette smoking significantly lowered the expected average annual increase in FEV1 (P = 0.015). On the basis of this analysis, it is estimated that if two children have the same initial FEV1, age, height, increase in height, and personal cigarette-smoking history, but the mother of one has smoked throughout the child's life whereas the mother of the other has not, the difference in the change in FEV1 over time in the exposed child, as compared with that in the unexposed child, will be approximately 28, 51, and 101 ml after one, two, and five years, respectively, or a reduction of 10.7, 9.5, and 7.0 per cent, respectively, in the expected increase. These results suggest that passive exposure to maternal cigarette smoke may have important effects on the development of pulmonary function in children.