A prospective study of mortality among middle-aged diabetic patients (the London cohort of the WHO Multinational Study of Vascular Disease in Diabetics) I: causes and death rates
A prospective study of mortality among middle-aged diabetic patients (the London cohort of the WHO Multinational Study of Vascular Disease in Diabetics) I: causes and death rates
复制标题
中年糖尿病患者死亡率的前瞻性研究（世界卫生组织糖尿病患者血管疾病跨国研究的伦敦队列）I：原因和死亡率
作者：
N. Morrish;L. Stevens;J. Head;J. Fuller;R. Jarrett;H. Keen
摘要 1975 年至 1987 年间，对世界卫生组织糖尿病血管疾病跨国研究伦敦队列的 497 名成员的死亡率进行了跟踪。在此期间，有 92 名患者死亡。最常见的死亡原因是心肌梗塞：36 人死亡（39.1%），心脏病占死亡人数的 51.1%，所有心血管疾病占 55.4%。肿瘤性疾病占死亡人数的 25%，糖尿病肾病占 5.4%。在 1 型（胰岛素依赖型）糖尿病和 2 型（非胰岛素依赖型）糖尿病中，男性的年龄标准化死亡率均高于女性。在第一个和第二个五年随访期的标准化死亡率中，2型糖尿病患者的男性高于女性，但1型糖尿病患者的女性高于男性。结果表明，在普通人群中观察到的女性生存优势可能会在2型糖尿病中持续存在，但在1型糖尿病中则不然。
SummaryThe 497 members of the London Cohort of the WHO Multinational Study of Vascular Disease in Diabetics have been followed for mortality from 1975 to 1987. During this period 92 patients died. The most common cause of death was myocardial infarction: 36 (39.1%) deaths, heart disease was responsible for 51.1% of deaths and all cardiovascular disease for 55.4%. Neoplastic disease accounted for 25% of the deaths and diabetic nephropathy for 5.4%. Age-standardised mortality rates were higher in men than in women in both Type 1 (insulin-dependent) diabetes and Type 2 (non-insulin-dependent) diabetes. Standardised mortality ratios for the first and second five year follow-up periods were higher for men than for women in Type 2 diabetes but were higher for women than men in Type 1. The results suggest that the female survival advantage seen in the general population may persist in Type 2 but not in Type 1 diabetes.