Impact of Intrahepatic Venovenous Shunt on Hepatic Venous Pressure Gradient Measurement

Impact of Intrahepatic Venovenous Shunt on Hepatic Venous Pressure Gradient Measurement
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DOI:
10.1016/j.jvir.2020.08.027
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发表时间:
2020-12-01
影响因子:
2.9
通讯作者:
Yang, Minjie
Yang, Minjie
中科院分区:
医学3区
文献类型:
--
作者:
Ma, Jingqin;Gong, Ximing;Yang, Minjie

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目的:为定量分析肝内静脉-静脉分流术(IHVS)对肝静脉压力梯度(HVPG)测量的影响,材料与方法:2015年至2019年,222例经颈静脉肝内门体分流术期间进行的HVPG测量符合本研究的条件。数字减影血管造影(DSA)软件通过时间-强度曲线对二维DSA序列的每个像素进行颜色编码,以分类IHVS。36.5%(81/222)的患者存在不同程度的IHVS。轻度IHVS发生率为10.8%(24/222),中度IHVS发生率为10.8%(24/222),重度IVHS发生率为14.9%(33/222)。17.78 mm Hg +/- 7.00 vs 24.89 mm Hg +/- 8.69,P =.001; HVPG:11.93 mm Hg +/- 5.76 vs 18.6 mm Hg +/- 6.85,P
Purpose: To quantitatively analyze the impact of intrahepatic venovenous shunt (IHVS) on hepatic venous pressure gradient (HVPG) measurement.Materials and Methods: From 2015 to 2019, 222 HVPG measurements performed during transjugular intrahepatic portosystemic shunt creation were eligible for this study. Digital subtraction angiography (DSA) software color-coded each pixel of a two-dimensional DSA series by time-intensity curve to classify IHVS. Different degrees of IHVS were found in 36.5% of patients (81/222). Mild IHVS was found in 10.8% of patients (24/222), moderate IHVS was found in 10.8% of patients (24/222), and severe IVHS was found in 14.9% of patients (33/222).Results: Mean wedged hepatic vein pressure (WHVP) and HVPG were significantly lower in patients with IHVS compared with patients without IHVS (WHVP: 17.78 mm Hg +/- 7.00 vs 24.89 mm Hg +/- 8.69, P =.001; HVPG: 11.93 mm Hg +/- 5.76 vs 18.6 mm Hg +/- 6.85, P