HEMODYNAMIC-EFFECTS OF SAN-HUANG-HSIEH-HSIN-TANG IN PATIENTS WITH ESSENTIAL-HYPERTENSION

HEMODYNAMIC-EFFECTS OF SAN-HUANG-HSIEH-HSIN-TANG IN PATIENTS WITH ESSENTIAL-HYPERTENSION
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DOI:
10.1142/s0192415x86000247
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发表时间:
1986-01-01
影响因子:
5.7
通讯作者:
HSIEH, MT
HSIEH, MT
中科院分区:
医学2区
文献类型:
--
作者:
CHEN, HC;HSIEH, MT

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中国古代的“三黄消心汤”(S-T)最初用于“上腹胀满、潮红、躁动、便秘、脉搏急促”的患者(公元前115年)。所有这些症状在高血压患者中都是常见的。我们评价了该方剂的降压和血流动力学作用,发现S-T能降低血压、总外周阻力、心率和心脏收缩力。S-T对心输出量和血容量无明显影响。
The ancient Chinese formula of "San-Huang-Hsieh-Hsin-Tang" (S-T) was originally used for patients with "epigastric fullness, flushing, restlessness, constipation and a hard pulse" (Chang 115 B.C.). All these symptoms are frequently observed in patients with essential hypertension. We assessed the antihypertensive and hemodynamic effects of this formula, and found that S-T decreased blood pressure, total peripheral resistance, heart rate and cardiac contractile force. S-T had no apparent effects on cardiac output and blood volume.