Use of Negative-Pressure Wound Therapy With Instillation and Dwell Time: An Overview
Use of Negative-Pressure Wound Therapy With Instillation and Dwell Time: An Overview
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DOI：
10.1097/prs.0000000000007607
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发表时间：
2021-01-01
影响因子：
3.6
通讯作者：
Behnam, Amir B.
中科院分区：
文献类型：
--
作者：
Faust, Elizabeth;Opoku-Agyeman, Jude L.;Behnam, Amir B.
负压伤口治疗（NPWT）的使用已成为伤口管理的既定疗法。NPWT技术有许多进步，包括NPWT滴注和留置（NPWTi-d）。NPWTi-d通过伤口清洁、冲洗和非切除清创促进伤口愈合。比较临床研究表明，NPWTi-d可缩短最终伤口愈合时间和住院时间。NPWTi-d-使用带“通”孔的网状开孔泡沫敷料（ROCF-CC）-已被认为可在手术清创之前或之后以及在手术清创不可选的情况下促进感染性物质（如斯劳和浓稠渗出液）的溶解、分离和清除。作者通过审查系统组件、拟定的作用机制、临床结局和当前共识指南，概述了NPWTi-d的使用。
The use of negative-pressure wound therapy (NPWT) has become an established therapy for wound management. There have been many advancements in the technology of NPWT including NPWT with instillation and dwell (NPWTi-d). NPWTi-d promotes wound healing by wound cleansing, irrigation, and nonexcisional debridement. NPWTi-d has been shown in comparative clinical studies to decrease the time to definitive wound healing and length of hospitalization. NPWTi-d-using a reticulated open-cell foam dressing with "through" holes (ROCF-CC)-has been postulated to facilitate solubilization, detachment, and elimination of infectious materials, such as slough and thick exudate, before or after operative debridement, and in cases where surgical debridement is not an option. The authors provide an overview on the use of NPWTi-d by reviewing the components of the system, proposed mechanism of action, clinical outcomes, and current consensus guidelines for its utilization.