LINKPHASE3: an improved pedigree-based phasing algorithm robust to genotyping and map errors

LINKPHASE3: an improved pedigree-based phasing algorithm robust to genotyping and map errors
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DOI:
10.1093/bioinformatics/btu859
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发表时间:
2015-05-15
期刊:
影响因子:
5.8
通讯作者:
Georges, Michel
Georges, Michel
中科院分区:
生物学3区
文献类型:
--
作者:
Druet, Tom;Georges, Michel

文献摘要

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Many applications in genetics require haplotype reconstruction. We present a phasing program designed for large half-sibs families (as observed in plant and animals) that is robust to genotyping and map errors. We demonstrate that it is more efficient than previous versions and other programs, particularly in the presence of genotyping errors.