Radiologic-Pathologic Conference of Children's Hospital Boston: New pulmonary nodules in a child undergoing treatment for a solid malignancy
Radiologic-Pathologic Conference of Children's Hospital Boston: New pulmonary nodules in a child undergoing treatment for a solid malignancy
复制标题
DOI：
10.1007/bf01403697
复制
发表时间：
1996-01-01
影响因子：
2.3
通讯作者：
Taylor, GA
中科院分区：
文献类型：
--
作者：
DAlessandro, MP;Kozakewich, HPW;Taylor, GA
患有实体恶性肿瘤的儿童在接受化疗时出现肺结节是临床上令人担忧的事件。这种病例的诊断不一定是转移性疾病，鉴别诊断应包括肉芽肿性疾病、肺不张、肺炎、炎性假瘤、错构瘤、放射性肺炎和闭塞性细支气管炎伴机化性肺炎。没有一致的放射学特征来帮助区分这些新病变的良恶性原因。然而，在首次发现病变后4-6周重复胸部CT可用于跟踪病变进展，并可能减少活检的需要。
The appearance of pulmonary nodules in a child with a solid malignancy undergoing chemotherapy is a clinically worrisome event. The diagnosis in such cases is not always metastatic disease, and the differential diagnosis should include granulomatous disease, atelectasis, pneumonia, inflammatory pseudotumor, hamartoma, radiation pneumonitis, and bronchiolitis obliterans with organizing pneumonia. There is no consistent radiologic feature to help distinguish benign from malignant causes of these new lesions. However, repeat chest CT 4-6 weeks after the lesions are first noted can be used to track lesion progression and may obviate the need for biopsy.