Respiratory effects of air pollution on children
Respiratory effects of air pollution on children
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DOI：
10.1002/ppul.23262
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发表时间：
2016-01-01
影响因子：
3.1
通讯作者：
Knibbs, Luke D.
中科院分区：
文献类型：
--
作者：
Goldizen, Fiona C.;Sly, Peter D.;Knibbs, Luke D.
全球疾病负担的很大一部分可直接或间接归因于暴露于空气污染。在胎儿发育和出生后早期的器官形成和肺部快速生长期间发生的接触尤其有害。在这篇最新的综述中，我们讨论了空气毒物对儿童呼吸系统健康的影响、暴露途径（重点是与幼儿相关的独特途径）、暴露评估方法及其局限性以及暴露对健康的不良后果。最后，我们指出在这方面的知识和研究需求的差距。需要更好地了解生命早期暴露于空气污染对健康的不利影响，以鼓励决策者减少这种暴露并改善人类健康。小儿肺醇。2016;51：94-108. (c)2015 Wiley Periodicals，Inc.
A substantial proportion of the global burden of disease is directly or indirectly attributable to exposure to air pollution. Exposures occurring during the periods of organogenesis and rapid lung growth during fetal development and early post-natal life are especially damaging. In this State of the Art review, we discuss air toxicants impacting on children's respiratory health, routes of exposure with an emphasis on unique pathways relevant to young children, methods of exposure assessment and their limitations and the adverse health consequences of exposures. Finally, we point out gaps in knowledge and research needs in this area. A greater understanding of the adverse health consequences of exposure to air pollution in early life is required to encourage policy makers to reduce such exposures and improve human health. Pediatr Pulmonol. 2016;51:94-108. (c) 2015 Wiley Periodicals, Inc.