On a path to accelerate access to Ebola vaccines: The WHO's research and development efforts during the 2014-2016 Ebola epidemic in West Africa
On a path to accelerate access to Ebola vaccines: The WHO's research and development efforts during the 2014-2016 Ebola epidemic in West Africa
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DOI：
10.1016/j.coviro.2016.03.008
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发表时间：
2016-04-01
影响因子：
5.9
通讯作者：
Kieny, Marie Paule
中科院分区：
文献类型：
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作者：
Henao-Restrepo, Ana Maria;Preziosi, Marie-Pierre;Kieny, Marie Paule
2014年和2015年期间，被视为国际关注的突发公共卫生事件的埃博拉疫情影响了一些西非国家。此次疫情凸显了研制埃博拉疫苗的必要性。这是一项前所未有的合作努力，在很大程度上建立在可进入临床阶段评估的一些候选疫苗的可用性上。世卫组织领导了一系列国际磋商和活动，作为对开发和评估埃博拉疫苗的前所未有的全球努力的贡献。世卫组织广泛征求意见，并立即促进与国际科学、伦理、监管、疫苗开发、公共卫生合作伙伴、工业界和资助者社区的互动，并参加了促进埃博拉疫苗评估的联盟。世卫组织还促进了关键活动，以确保获得许可的埃博拉疫苗的最佳政策和部署。世卫组织召集了一个广泛的全球专家联盟，以制定一份蓝图和一个加速研发的平台，以避免流行病全面爆发。
During 2014 and 2015 an outbreak of Ebola deemed a Public Health Emergency of International Concern affected a number of West African countries. The outbreak underscored the need for a vaccine against Ebola. An unprecedented and to great extent collaborative effort built on the availability of a number of candidate vaccines that could enter into clinical phase evaluation. A series of international consultations and activities were led by WHO as a contribution to the unprecedented global efforts to develop and assess an Ebola vaccine. WHO consulted widely, and immediately fostered interactions with the international scientific, ethics, regulatory, vaccine development, public health partners, industry and funders' communities and participated in consortia to facilitate Ebola vaccine assessments. WHO also fostered key activities to ensure the optimal policy and deployment of Ebola vaccines, if licensed. WHO has convened a broad global coalition of experts to develop a Blueprint and a platform for accelerated R&D, in order to avert full-blown epidemics.