Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996-2007)
Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996-2007)
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DOI：
10.1016/j.ajog.2010.03.029
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发表时间：
2010-09-01
影响因子：
9.8
通讯作者：
Adzick, N. Scott
中科院分区：
文献类型：
--
作者：
Wilson, R. Douglas;Lemerand, Kerrie;Adzick, N. Scott
目的：评估妊娠后并发开放性母胎手术 (OMFS) 的妇女的生殖和妇科结局。 研究设计：回顾性审查确定了来自同一机构 (1996-2007) 的 93 名患有 OMFS 的妇女。向女性发送了同意书和调查问卷。获得人类受试者保护委员会机构审查委员会的批准。结果：总回报率为57.3%。报告的怀孕总数为 47 例，其中 36 例在妊娠 20 周后分娩。子宫裂开和破裂率分别为14%和14%。随后的 4 次妊娠均出现胎儿异常。 98% 的后续妊娠均能正常受孕。 8 名女性报告了妇科问题，包括不孕、腹痛以及卵巢和子宫因素。 结论：随后怀孕时子宫开裂 (14%) 和破裂 (14%) 的生殖结局仍然是 OMFS 的主要咨询问题。接受 OMFS 的女性的生育能力和妇科因素似乎并未增加。
OBJECTIVE: The reproductive and gynecologic outcomes for women after the pregnancy complicated by open maternal-fetal surgery (OMFS) were evaluated.STUDY DESIGN: The retrospective review identified 93 women with OMFS from a single institution (1996-2007). Consent and questionnaires were sent to women. Institutional review board approval was obtained from the Committee for Protection of Human Subjects.RESULTS: The total return rate was 57.3%. Total pregnancies reported were 47, with 36 delivering after 20 weeks' gestation. The uterine dehiscence and rupture rates were 14% and 14%, respectively. Fetal anomalies occurred in 4 subsequent pregnancies. Normal conception occurred in 98% of subsequent pregnancies. Gynecologic issues were reported by 8 women, with infertility, abdominal pain, and ovarian and uterine factors.CONCLUSION: The reproductive outcomes of uterine dehiscence (14%) and rupture (14%) in a subsequent pregnancy continue to be a major counseling issue for OMFS. Fertility and gynecologic factors do not appear to be increased for women undergoing OMFS.