PSD502 improves ejaculatory latency, control and sexual satisfaction when applied topically 5 min before intercourse in men with premature ejaculation: results of a phase III, multicentre, double-blind, placebo-controlled study
PSD502 improves ejaculatory latency, control and sexual satisfaction when applied topically 5 min before intercourse in men with premature ejaculation: results of a phase III, multicentre, double-blind, placebo-controlled study
复制标题
DOI：
10.1111/j.1464-410x.2009.08456.x
复制
发表时间：
2009-04-01
影响因子：
4.5
通讯作者：
Wyllie, Michael G.
中科院分区：
文献类型：
--
作者：
Dinsmore, W. Wallace;Wyllie, Michael G.
确定在性交前5分钟局部施用PSD 502对患有根据国际性医学学会（ISSM）定义的终身早泄（PE）的男性的早泄指数（IPE）和阴道内射精潜伏时间（IELT）的影响;次要目的是评价PSD 502在PE患者及其性伴侣中的安全性和耐受性。年龄> 18岁，稳定异性恋，一夫一妻制关系，并且根据精神疾病诊断和统计手册第四版（文本修订版）标准和ISSM定义诊断为终身PE，同意（及其伴侣）进入研究的基线期。记录IELT为
To determine the effect of PSD502 applied topically 5 min before intercourse on the Index of Premature Ejaculation (IPE) and intravaginal ejaculatory latency time (IELT) of men with lifelong premature ejaculation (PE) defined according to the International Society of Sexual Medicine (ISSM) definition; secondary objectives were to evaluate the safety and tolerability of PSD502 in patients with PE, and their sexual partners.Men aged > 18 years, in stable heterosexual, monogamous relationships, and with lifelong PE diagnosed according to both the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (text revision) criteria and the ISSM definition, consented (together with their partners) to enter the baseline period of the study. Patients who documented an IELT of