The relationship of childhood to adult blood pressure: longitudinal study of juvenile hypertension in Lithuania
The relationship of childhood to adult blood pressure: longitudinal study of juvenile hypertension in Lithuania
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DOI：
10.1097/00004872-200018050-00004
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发表时间：
2000-05-01
影响因子：
4.9
通讯作者：
Shatchkute, A
中科院分区：
文献类型：
--
作者：
Klumbiene, J;Sileikiene, L;Shatchkute, A
目的 评估儿童期至成年期的血压变化以及预测成人血压的能力。设计对一组儿童的基线数据进行纵向研究并进行20年后的跟踪调查。设置对立陶宛考纳斯镇学龄儿童及其后居民的流行病学调查。参与者来自15所学校，占1964年出生的所有12岁和13岁儿童的25%。 考纳斯。第一次调查 (n = 1082) 于 1977 年进行。1997 年对同一人群进行了重新调查 (n = 505)。提供了参与第一次和最近一次调查的 217 名男性和 288 名女性的数据。主要结果测量 32-33 岁的收缩压和舒张压。结果在两次调查之间的 20 年里，男性血压升高幅度高于女性。估计儿童和成人血压水平之间具有统计学上的显着相关性（男性收缩压 r = 0.40，女性 r = 0.24；男性舒张压 r = 0.14，女性 r = 0.34）。数据的逐步回归分析表明，成人血压的最佳预测因素是儿童时期的初始血压水平以及男性和女性 20 年间体重指数的变化。其他因素的预测性较差。 结论 儿童血压与成人水平相关，并且与体重指数的变化一起，是成人血压的重要预测因素。 J Hypertens 2000，18：531-538 (C) Lippincott Williams & Wilkins。
Objective To assess changes in blood pressure from childhood to adulthood and the ability to predict adult blood pressure.Design Longitudinal study of a cohort of children with baseline data and a follow-up survey after 20 years.Setting Epidemiological survey of schoolchildren and subsequent inhabitants of Kaunas, a town in Lithuania.Participants The children came from 15 schools and accounted for 25% of all 12- and 13-year-old children born in 1964 in Kaunas. The first survey (n = 1082) was carried out in 1977. The same population was re-examined in 1997 (n = 505). Data from 217 men and 288 women, who participated in both the first and the most recent surveys, is presented.Main outcome measures Systolic and diastolic blood pressure at the age of 32-33 years.Results In the 20 years between the two surveys blood pressure increased more in men than in women. Statistically significant correlation between childhood and adult blood pressure levels was estimated (for systolic blood pressure r = 0.40 in men and r = 0.24 in women; for diastolic blood pressure r = 0.14 in men and r = 0.34 in women). Stepwise regression analysis of the data showed that the best predictors of adult blood pressure were the initial childhood blood pressure levels and change in BMI during the 20-year period for both men and women. Other factors were less predictive.Conclusions Childhood blood pressure is related to adult levels and, together with changes in body mass index, is a significant predictor of adult blood pressure. J Hypertens 2000, 18:531-538 (C) Lippincott Williams & Wilkins.