EVALUATION OF TYPHIDOT (IGM) IN EARLY AND RAPID DIAGNOSIS OF TYPHOID FEVER

EVALUATION OF TYPHIDOT (IGM) IN EARLY AND RAPID DIAGNOSIS OF TYPHOID FEVER
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伤寒早期快速诊断中伤寒 (IGM) 的评估

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发表时间:
2011
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通讯作者:
S. Shah
S. Shah
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作者:
S. Shah

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引言 还延迟诊断等开始适当 5 伤寒被广泛认为是一种主要的公共疗法。发展中国家的健康问题。它是由伤寒杆菌引起的严重全身感染。这项研究在阿伯塔巴德的背景下非常重要,该地区疾病在印度次大陆流行,南伤寒已导致大量患者前往东亚、非洲、中东、南部和中部三级护理医院就诊,因为他们中的大多数人饮用美国的纯净水供应和来自管井和深井的原水以及1个污水控制设施的供应不足。据估计,发烧上厕所后没有正确洗手的伤寒发病率约为 2200 万块肥皂。此外,他们大多数是文盲,生活环境卫生差,社会经济状况较差,每年至少有20万人死亡。从而进一步诱发疾病 该疾病可能发生在所有年龄段,其中患病率最高 3 岁。因此,我们进行了这项研究,特别是在儿童中发现了需要的发生率。根据世界卫生组织(WHO)的可靠实验室测试,可以早期快速诊断伤寒的总体发病率。巴基斯坦每 4 年每 10 万人中就有 412 例伤寒病例。伤寒已知是通过血培养分离伤寒沙门氏菌 (S.typhi) 与显着的发病率和死亡率相关,因为仍用作伤寒的金标准测试,但新出现的沙门氏菌多重耐药菌株和伤寒早期和快速诊断中伤寒 (IGM) 的原始 PROF-1726 伤寒评估
.INTRODUCTION also delay in diagnosis and so start of appropriate 5 Typhoid fever is widely recognized as a major public therapy . health problem in developing countries. It is a severe systemic infection caused by Salmonella typhi. The This study was important in context of Abbottabad where disease is endemic in the Indian sub-continent, Southtyphoid fever had caused large number of patients to visit East Asia, Africa, the Middle-East, South and Central tertiary care hospitals because majority of them drank America, where provision of pure water supplies and raw-water from tube-wells and deep-borred wells and 1 sewage control are inadequate . Incidence of typhoid also didn’t wash hands properly after using toilets with fever has been estimated as approximately 22 million soap. In addition, most of them are illiterate, living in 2 unhygienic surroundings and have poor socio-economic cases with at least 200,000 deaths occurring annually . status hence further predisposing for disease The disease may occur in all ages, with the highest 3 prevalence. Therefore, we conducted this study in need incidence found particularly in children . According to of a reliable laboratory test for early and rapid diagnosis WHO (World Health Organization), the overall incidence of typhoid fever. of typhoid fever is 412 cases per 100,000 population per 4 year in Pakistan . Typhoid fever is known to be Isolation of Salmonella typhi (S.typhi) via blood culture is associated with significant morbidity and mortality due to still used as gold standard test for typhoid fever, but emerging multidrug-resistant strains of salmonellae and ORIGINAL PROF-1726 TYPHOID FEVER EVALUATION OF TYPHIDOT (IGM) IN EARLY AND RAPID DIAGNOSIS OF TYPHOID FEVER