What determines subjective health status in patients with chronic obstructive pulmonary disease: importance of symptoms in subjective health status of COPD patients
What determines subjective health status in patients with chronic obstructive pulmonary disease: importance of symptoms in subjective health status of COPD patients
复制标题
DOI：
10.1186/1477-7525-6-115
复制
发表时间：
2008-12-18
影响因子：
3.6
通讯作者：
Wahl, Astrid Klopstad
中科院分区：
文献类型：
--
作者：
Bentsen, Signe Berit;Henriksen, Anne Hildur;Wahl, Astrid Klopstad
背景资料：慢性阻塞性肺疾病（COPD）患者的主观健康状况是生理和心理社会因素相互作用的结果。然而，对COPD患者主观健康状况的多变量解释了解甚少。本研究的目的是通过评估年龄和性别、预测FEV 1%、血氧饱和度、呼吸困难、焦虑和抑郁、运动能力等背景变量与身心健康之间的关系，探索决定COPD主观健康状况的因素。方法：本研究采用横断面设计，包括100名COPD患者（51%男性，平均年龄66.1岁）。肺功能通过预测FEV1%评估，经皮脉搏血氧仪评估氧饱和度，St乔治呼吸问卷和医院焦虑抑郁量表评估症状，递增穿梭步行试验评估身体功能，SF-36健康调查评估主观健康状况。结果：老年患者呼吸困难较少，女性患者焦虑较多（p < 0.050）。女性、老年患者、FEV1%预测值较低的患者和抑郁程度较重的患者的身体功能较低（p < 0.050）。FEV1%预测值较高、呼吸困难较多、焦虑或抑郁较多的患者主观健康状况较低（p < 0.050）。结论：症状对COPD患者的主观健康状况的影响比人口统计学、生理变量和身体功能更重要。在治疗和护理这些患者时应考虑这些发现。
Background: Subjective health status is the result of an interaction between physiological and psychosocial factors in patients with chronic obstructive pulmonary disease (COPD). However, there is little understanding of multivariate explanations of subjective health status in COPD. The purpose of this study was to explore what determines subjective health status in COPD by evaluating the relationships between background variables such as age and sex, predicted FEV1%, oxygen saturation, breathlessness, anxiety and depression, exercise capacity, and physical and mental health.Methods: This study had a cross-sectional design, and included 100 COPD patients (51% men, mean age 66.1 years). Lung function was assessed by predicted FEV1%, oxygen saturation by transcutaneous pulse oximeter, symptoms with the St George Respiratory Questionnaire and the Hospital Anxiety and Depression Scale, physical function with the Incremental Shuttle Walking Test, and subjective health status with the SF-36 health survey. Linear regression analysis was used.Results: Older patients reported less breathlessness and women reported more anxiety (p < 0.050). Women, older patients, those with lower predicted FEV1%, and those with greater depression had lower physical function (p < 0.050). Patients with higher predicted FEV1%, those with more breathlessness, and those with more anxiety or depression reported lower subjective health status (p < 0.050). Symptoms explained the greatest variance in subjective health status (35%-51%).Conclusion: Symptoms are more important for the subjective health status of patients with COPD than demographics, physiological variables, or physical function. These findings should be considered in the treatment and care of these patients.