HISTOLOGICAL AND RADIOGRAPHIC ASSESSMENT OF WELL-FUNCTIONING POROUS-COATED ACETABULAR COMPONENTS - A HUMAN POSTMORTEM RETRIEVAL STUDY
HISTOLOGICAL AND RADIOGRAPHIC ASSESSMENT OF WELL-FUNCTIONING POROUS-COATED ACETABULAR COMPONENTS - A HUMAN POSTMORTEM RETRIEVAL STUDY
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DOI：
10.2106/00004623-199306000-00003
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发表时间：
1993-06-01
影响因子：
5.3
通讯作者：
BRAGDON, C
中科院分区：
文献类型：
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作者：
ENGH, CA;ZETTLSCHAFFER, KF;BRAGDON, C
尸检发现9个多孔涂层髋臼假体。所有部件都已在我们机构植入，并已在原位放置了平均50个月(从17个月到87个月不等)。临床记录显示，在死亡时，所有人的功能都很好，临床X光照片显示，所有人都很稳定。使用标准背向散射扫描电子显微镜来定量骨长入多孔涂层的量。对于每种成分，骨-金属界面的组织学外观与临床X线片上的外观进行了比较。光镜下观察非骨化区。每一种成分都有骨生长到多孔涂层中，内长入的骨平均占被检查区域的32%(范围为3%至84%)。在发生骨长入的区域，平均面密度为48%(范围为26%至65%)。使用X线片总是导致低估了间隙区域的存在和高估了骨对位的发生。当纤维组织出现在非骨化区时，其密度极高且组织良好。在光镜检查范围内，非骨化区未见肉芽肿形成。这一点特别令人鼓舞，因为纤维组织-骨骼界面似乎阻止了颗粒碎片的沉积。
Nine porous-coated acetabular components were retrieved post mortem. All components had been inserted at our institution and had been in situ for a mean of fifty months (range, seventeen to eighty-seven months). Clinical records revealed that all had been functioning well at the time of death, and clinical radiographs showed signs that all had been stable. Standard backscattered scanning electron microscopy was used to quantitate the amount of bone ingrowth into the porous coating. For each component, the histological appearance of the bone-metal interface was compared with the appearance on clinical radiographs. Light microscopy was used to study the non-ossified areas. Every component had growth of bone into the porous coating, with the ingrowth occupying a mean of 32 per cent (range, 3 to 84 per cent) of the fields that were examined. In areas where bone ingrowth had occurred, the mean area density was 48 per cent (range, 26 to 65 per cent). Use of radiographs consistently led to an underestimation of the presence of gap areas and an overestimation of the occurrence of bone apposition. When fibrous tissue was present in non-ossified areas, it was extremely dense and well organized. Within the limits of light microscopic examination, there was no evidence of granulomatous formation in the non-ossified regions. This is particularly encouraging since the fibrous tissue-bone interfaces seem to prohibit the deposit of particulate debris.