Incidence pattern of colorectal cancer in Korea by subsite of origin

Incidence pattern of colorectal cancer in Korea by subsite of origin
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DOI:
10.3346/jkms.2000.15.6.675
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发表时间:
2000-12-01
影响因子:
4.5
通讯作者:
Ahn, YO
Ahn, YO
中科院分区:
医学4区
文献类型:
--
作者:
Kim, DH;Shin, MH;Ahn, YO

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有人认为,基于其起源亚位点的独特特征,结直肠癌可能不是一种同质的疾病实体。 1993 年至 1995 年间,从首尔癌症登记处获得了 4,987 例结直肠癌的发病率数据。对年龄、性别和亚部位特异性发病率进行了比较。男性和女性的年龄标准化总结直肠癌年发病率分别为每 10 万人 26.1 例和 18.0 例。两种性别的结肠癌和直肠癌发病率没有明显差异(结肠癌与直肠癌:男性 12.8 vs 13.2,女性 9.3 vs 8.6)。男性右半结肠的发病率略高于女性,左半结肠的差异更大(男性与女性:右半结肠3.5 vs 3.0,左半结肠4.7 vs 2.9)。右半结肠与左半结肠的发病率相比,60岁及以上老年人中女性右半结肠发病率较高,40岁及以下老年人右半结肠发病率较低,而男性则相反。需要更多的分析方法来确定哪些因素与结直肠癌发病率的这些描述性结果相关。
It has been suggested that colorectal cancer might not be one homogenous disease entity, based on the distinctive characteristics of its subsite of origin. Incidence data on 4,987 colorectal cancer were obtained from the Seoul Cancer Registry between 1993 and 1995. Age, sex, and subsite-specific incidence rates were compared. The age-standardized annual incidence rates of total colorectal cancer were 26.1 and 18.0 per 100,000 for men and women, respectively. There were no appreciable difference in the rates of colon and rectal cancer for either sex (colon vs rectum: 12.8 vs 13.2 for men, 9.3 vs 8.6 for women). The incidence rate of right colon was slightly higher in men than in women, and this discrepancy became even greater in left colon (men vs women: 3.5 vs 3.0 for right colon, 4.7 vs 2.9 for left colon). When the incidence rate of right colon was compared with that of left colon, women had a higher rate in the right colon among the elderly, aged 60 yr and over and a lower rate at age 40 yr or less, while the opposite was observed for men. More analytic approaches are needed to identify which factors are related with these descriptive results in colorectal cancer incidence.