Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data.
Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data.
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DOI：
10.1002/jms.3672
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发表时间：
2016-07-01
期刊：
影响因子：
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通讯作者：
Tiwari, H K
中科院分区：
文献类型：
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作者：
Barnes, S;Benton, H P;Tiwari, H K
代谢组学可能是组学领域中最具挑战性的，因为生物体代谢组的复杂性及其变化的速度非常快。当一个人开始研究新陈代谢时，有许多动态变量可以影响新陈代谢，必须考虑。认识到从事新陈代谢研究的研究人员面临的实验挑战，阿拉巴马大学伯明翰分校（University of Alabama at Birmingham）这样的研讨会已经成立，以提供教学指导。UAB课程培训材料的摘要将以两部分专题教程的形式发布。在本月的第一部分中，作者讨论了良好的实验设计和样品收集和处理的细节。在即将出版的第二部分中，作者详细讨论了数据分析的各个方面。
Metabolomics is perhaps the most challenging of the -omics fields, given the complexity of an organism's metabolome and the rapid rate at which it changes. When one sets out to study metabolism there are numerous dynamic variables that can influence metabolism that must be considered. Recognizing the experimental challenges confronting researchers who undertake metabolism studies, workshops like the one at University of Alabama at Birmingham have been established to offer instructional guidance. A summary of the UAB course training materials is being published as a two-part Special Feature Tutorial. In this month's Part I the authors discuss details of good experimental design and sample collection and handling. In an upcoming Part II, the authors discuss in detail the various aspects of data analysis.