Importance of lean mass in the interpretation of total body densitometry in children and adolescents
Importance of lean mass in the interpretation of total body densitometry in children and adolescents
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DOI：
10.1016/s0022-3476(03)00187-2
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发表时间：
2003-07-01
影响因子：
5.1
通讯作者：
Cowell, CT
中科院分区：
文献类型：
--
作者：
Högler, W;Briody, J;Cowell, CT
Objective Most studies that use total body dual energy x-ray absorptiometry (DEXA) in children rely on areal bone mineral density (BMD = bone mineral content [BMC]/bone area [BA]) and compare the output with age- and sex-specific normative data. Because this approach is prone to size-related misinterpretation, this study focuses on the interrelations among BMC, body size (height), and lean tissue mass (LTM).Study design This cross-sectional study presents normative total body LTM data in relation to height and BMC for 459 healthy white subjects (249 female), 3 to 30 years of age. Guidelines for DEXA interpretation in children are provided and illustrated for patients with growth hormone deficiency (n = 5) and anorexia nervosa (n = 5).Results LYM/height tended to be greater in male than in girls. The BMC/LTM ratio was greater in female than in boys (P
